UI Zbrush 2021

If you have an old version of Zbrush this should help you have a really usefull interface to start sculpting.

Masks and selection brushes on the left side
Sculpture, move and insert brushes on the lower part
Pan, move and zoom, Materials and render on the right side
Brush, boolean and sculptris settings on the upper part

Also theres a Special window called "Rokus Tools" that has all the most used featured on Zbrush.

Hope this helps you to create better and faster!